anti-thyroid peroxidase (anti-tpo)
ImmunologyBlood sampleResults 2-3 daysNo fasting
Anti-Thyroid Peroxidase (Anti-TPO)
Measures antibodies against thyroid peroxidase to help detect autoimmune thyroid disease. Useful when thyroid function tests are abnormal or autoimmune thyroiditis is suspected.
Sample
Blood
Results
2-3 days
Fasting
Not required
Follow-up
Optional add-on
What this test detects
Anti-thyroid peroxidase antibody (Anti-TPO)
ELISA · serum
Quantitative · IU/mL
When to get this test
Suspected autoimmune thyroiditis
Helps confirm Hashimoto's thyroiditis or Graves' disease as a cause of thyroid dysfunction.
Abnormal thyroid function
Adds context when TSH, T3, or T4 results are out of range.
Goiter or thyroid symptoms
Supports evaluation of an enlarged thyroid or symptoms like fatigue and weight changes.
How to prepare
01
No special preparation needed.
Common questions
What does a positive Anti-TPO mean?
Raised levels suggest your immune system is reacting against your thyroid, which is common in autoimmune thyroid conditions.
Is this the same as a thyroid function test?
No. Anti-TPO checks for antibodies, while TSH and T4 measure how well your thyroid is working. They are often done together.